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Yes, this non-nutritive sweetener has been approved as a safe ingredient by the U.S. Food and Drug Administration (FDA) and European Food Safety Authority (EFSA), as well as Joint FAO/WHO Expert Committee on Food Additives (JECFA).

FDA
Neotame may be safely used as a sweetener and flavor enhancer in food (2). The ADI is 0.3mg/kg bw/d. (3)

EFSA
Neotame (E961) is listed in Commission Regulation (EU) No 231/2012 as an authorised food additive and categorized in “Sweeteners” (4).

Safety re-evaluation in 2007
After the studies of genotoxicity, carcinogenicity, teratogenicity, reproductive and developmental toxicity, along with the degradation products researches, EFSA concluded it was not of safety concern when neotame is intended to be used as a sweetener and flavour enhancer and an Acceptable Daily Intake (ADI) of 0-2 mg/kg bw/day was established. (5)

Approved uses
When used as a sweetener, neotame is commonly used in energy-reduced or no-added-sugar products with the maximum usage ranges from 2-200mg/kg; or the use levels are “quantum satis” in table-top sweeteners in liquid/powder/tablets.
When used as a flavour enhancer, its maximum usage is 2mg/kg. (6)
UK Food Standards Agency
Categorized in “Sweeteners” (7)

Food Standards Australia New Zealand

It is approved ingredient in Australia and New Zealand with the code number 961. (8)

JECFA
Function Class: food additives, sweetener, flavor enhancer. (9)

Acceptable daily intake: ADI “0-2mg/kg bw” set in 2003. (10)

http://www.chinafooding.com/Neotame

L-Tartaric Acid is widely present in fruits, especially grapes. L-Tartaric Acid is the cheapest of the optical activity of tartaric acid, L-Tartaric Acid is often referred to as "natural tartaric acid." Industry, L-Tartaric Acid are still the main or even sole source of natural products. Wine industry by-products of tartar, acid treatment can be obtained by L-Tartaric Acid. Italy is the worlds L-Tartaric Acid largest producer of this wine made ​​with the size of the country are not unrelated.

L-Tartaric Acid maximum use of the beverage additive. Then the drug industry raw materials. In modern organic synthesis is very important chiral ligands and hand temper, L-Tartaric Acid used to produce many well-known chiral catalysts, and E334 as a chiral source to synthesize complex natural product molecules. L-Tartaric Acid is also an antioxidant, has been applied in the food industry.

http://www.chinafooding.com/L-Tartaric_Acid

Yes, it has been approved as a safe ingredient by U.S. Food and Drug Administration (FDA), European Food Safety Authority (EFSA), as well as Joint FAO/WHO Expert Committee on Food Additives (JECFA).

FDA
L-(+)-tartaric acid obtained from wine making is generally recognized as safe (GRAS) as a direct human food ingredient and can be used as a firming agent, flavor enhancer, flavoring agent, pH control agent and humectant in food with no limitation other than current good manufacturing practice. (4)

EFSA
L-tartaric acid (E334) is listed in Commission Regulation (EU) No 231/2012 as an authorised food additive and categorized in “Additives other than colours and sweeteners” (5).

Approved uses
E334 is listed in the group I which means most of its applications are not specific. The following food may contain with L-tartaric acid:

Canned or bottled fruit and vegetables
Jam, jellies and marmalades and sweetened chestnut purée
Cocoa and Chocolate products
Fresh (pre-cooked) pasta
Potato Gnocchi
Table-top sweeteners in tablets
Biscuits and rusks and baby foods for infants and young children
UK Food Standards Agency
Categorized in “Others” (6)

Food Standards Australia New Zealand
It is an approved ingredient in Australia and New Zealand with the code number 334. (7)

JECFA
Function Class: food additives, flavouring agent, acid, antioxidant synergist, sequestrant. (8) (9)

Acceptable daily intake: Group ADI “30 mg/kg bw” set in 1977 for it and its salts of sodium, potassium, and potassium–sodium. (10)

http://www.chinafooding.com/L-Tartaric_Acid

(1) Food Grade: Bleach agent (e.g. candies, cake, bamboo shoots, etc); Loose agent (e.g. bread, cracker etc); Antiseptic and germicide (e.g. fruit juice, tinned food, brews, the cereals food is defended storage etc); Inhibitor and freshen agent (e.g. day lily, seafood, fruit and vegetable etc).

(2) Industry Grade: Mordant of printing and dyeing; Dechlorinate of textile after bleaching; Sulphonated agent and reducer of chemical industry and pharmacy; Bleach of paper pulp, bamboo and timber bleach of Stap; Treatment agent of waste water; Rubber solidifying agent Perfume industry is served as hydro carbon perfume aldehyde.

http://www.chinafooding.com/Sodium_Metabisulfite

Yes, it almost has no side effects and the safety has been approved by the U.S. Food and Drug Administration (FDA) and European Food Safety Authority (EFSA), as well as the Joint FAO/WHO Expert Committee on Food Additives (JECFA).

FDA
Sodium metabisulfite is generally recognized as safe (GRAS) when used as a preservative except in meats, foods recognized as a source of vitamin B1 and fresh fruits or vegetables. (2)

EFSA
Sodium metabisulfite (E223) is listed in Commission Regulation (EU) No 231/2012 as an authorised food additive and categorized in “ additives other than colours and sweeteners” (3).

Safety re-evaluation in 2016

EFSA concluded that the current group ADI of 0.7 mg expressed as SO2 equivalent/kg bw per day for E220-E228 was temporary and would be re-evaluated due to the uncertainties and limitations in the database (4)

Approved uses
Its application is listed together with sulfur dioxide (E220), sodium sulfite (E221), sodium bisulfite (E222), potassium metabisulfite (E 224), calcium sulfite (E226), calcium bisulfite (E227) and potassium bisulfite (E228) and with the maximum use levels “10-2000 mg/kg”.

The following food may contain it (5):

Fresh, Peeled, cut and shredded, Frozen, Dried fruit and vegetables: such as table grapes, peeled potatoes, frozen and deep-frozen potatoes, dried coconut, dried mushrooms, dried ginger, dried tomatoes, dried apples, pears and bananas
Jams, jellies and mermelades
Dry biscuits
Beer and malt beverages
Cider and perry
Fruit wine and made wine
UK Food Standards Agency
Categorized in “Preservatives” (6)

Food Standards Australia New Zealand
It is an approved ingredient in Australia and New Zealand with the code number 223. (7)

JECFA
Function Class: food additives, antioxidant, flour treatment agent, preservative. (8)

Acceptable daily intake: ADI “0-0.7 mg/kg bw” set in 1998. (9)

http://www.chinafooding.com/Sodium_Metabisulfite